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KMID : 0980120220200010001
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Annals of Phlebology
2022 Volume.20 No. 1 p.1 ~ p.5
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Practical Use of Venoactive Drugs for Chronic Venous Disease in Korea
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Yun Sang-Chul
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Abstract
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Venoactive drugs can be used as a first-line treatment in all stages of chronic venous disease. In a more advanced stage, drugs can be used together with surgery or endovascular procedures. However, there is a lack of correlation between these clinical symptoms and varicose veins, so surgical treatment is recommended for patients with C2 or higher who are accompanied by symptoms and reflux. In other patients, with non-varicose pain in mind, first, conservative treatment should be provided to control symptoms. Currently used drugs are flavonoids including diosmin, micronized purified flavonoid fraction, rutin and troxerutin, and saponins including horse chestnut seed extract and Ruscus extract such as butcher’s broom, anthocyans, and synthetic drugs. There is a difference in the mechanism of action of each drug, and these drugs seem to be selectively used according to the symptoms mentioned by patients. The drug indications according to the guidelines and research and precautions are summarized in this review.
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KEYWORD
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Medical therapy, Chronic venous disease, Clinical practice guideline, Varicose vein, Drugs
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